PRATHAMASENSE GENOSENSOR

PRATHAMASENSE GENOSENSOR device provides ultrafast detection of microbial infection and Antimicrobial Resistance in just 90 minutes.

RAMJA GENOSENSOR has developed a fast, simple, and cost-effective solution for all hospitals, laboratories, and remote areas: a noble paper-based system that detects microbial infection and antimicrobial resistance within 2 hours. Our device is ultrasensitive, gene specific, portable, precise, compact, and user-friendly in almost every way. Unlike existing experiments (2-3 days result waiting) however, the PRATHAMASENSE gives results in less than 2 hours, saving both lives and money for hospitals. It is cost-efficient than conventional research approaches such as culture and PCR as it can reduce cost, efforts & resources by huge margin.

Our fight against infection

Infection is a major concern, particularly in the intensive care unit (ICU), where approximately 60-80% of patients develop harmful infections including catheter-related bloodstream infections, ventilator-associated pneumonia, and catheter-associated urinary tract infections. Because of the high infection rates, every single patient in the ICU is screened. Since a one-hour delay in care will raise death rates by up to 16% in vital cases, time is important. Standard detection techniques, on the other hand, require 2-5 days to produce results and physicians are forced to treat the infection with synthetic antibiotics, which does further damage to the patient in terms of antibiotic resistance. Antibiotic resistance is often linked to the excessive use of broad-spectrum antimicrobial agents, with more than 80% of all ICU patients receiving antibiotics during their stay.

Our Technology at a glance

Currently, there are over 4-5 techniques available in the world (culture, PCR, MALDI, Sequencing), all of those are time-consuming (2-5 days to get a result), expensive, difficult to execute, and require a team of experts (Scientist, Ph.D., M.D., M.Sc., Technician, 8-10 people). As a result of these current delayed procedures, doctors begin prophylactic antibiotics, causing antibiotic resistance and a high risk of death in ICU and other diseases in patients. So, for a country like India, we need a solution that is fast, gene specific, culture independent, cost-effective, and user-friendly, and that can have a quick outcome for patients while reducing the risk of death from sepsis and Multiple organ dysfunction syndrome (MODS).

RAMJA GENOSENSOR is a Med-Tech Indian Company that offers highly accurate and innovative paper-based technology for the detection of microbial infection and antibiotic resistance. Our team at RAMJA GENOSENSOR has developed INDIA’s first Paper Biosensor-based microbial infection and antibiotic susceptibility device - PRATHAMASENSE, that can produce results in 90 minutes, which is cost-effective in terms of setup and can be performed at room temperature on a table, reducing infrastructure costs.

Our unique Panels are in sync with WHO (World health organisation) panel

WHO (World health organisation) priority pathogens list for R&D of new antibiotics

Priority 1: CRITICAL AMR Panel
Acinetobacter baumannii, carbapenem-resistant
Pseudomonas aeruginosa, carbapenem-resistant
Enterobacteriaceae, carbapenem-resistant, ESBL-producing
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Our Panels

ANTIMICROBIAL RESISTANCE KIT (MODEL NO:- PG/IVD/AMR-001)

Colistin
- MCR-1

ESBL
- CTX-M

Methicillin
- Mec-A

Vancomycin Resistance
- Van A/B

Carbapenemase
- KPC
- NDM
- OXA-48
- OXA-23
- IMP
- VIM
- Acinetobacter baumannii (Res.)

CARBAPENEMASE PANEL (MODEL NO :- PG/IVD/AMR-002)

OXA-48

OXA-23

SMART TYPHOID PANEL (MODEL NO :- PG/IVD/TP-001)

Thyroid Detection
- TTR gene
- STG gene
- Flg-1 gene
- Flg-2 gene

Antimicrobial Resistance Detection
- Gyrase resistance (gyrA)
- Topoisomerase resistance (Par C)

PAN TYPHOID PANEL (MODEL NO :- PG/IVD/SL-001)

Typhoid Detection
- TTR gene
- STG gene
- Flg-1 gene
- Flg-2 gene

Antimicrobial Resistance Detection
- Gyrase resistance (gyrA)
- Topoisomerase resistance (Par C)
- ESBL resistance (CTX-M)

URINARY TRACT INFECTION (UTI) PANEL (MODEL NO :-PG/IVD/UTI-001)

Gram Negative Bacteria
- Escherichia coil
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
- Acinetobacter baumannii
- Proteus mirabills

Gram Positive Bacteria
- Staphylococcus aureus
- Enterococcus faecalis
- Staphylococcus saprophyticus

SMART SEPSIS PANEL (MODEL NO:- PG/IVD/SP-001)

Bacterial Species

Gram Negative Bacteria
- E coli
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
- Acinetobacter baumannii

Gram Positive Bacteria
- Staphylococcus aureus
- Enterococcus faecalis
- Staphylococcus saprophyticus

Fungus Species

Yeast
- Candida albicans

Carbapenemase
- KPC
- NDM
- OXA-48

Coilstin
- MCR-1

ESBL
- CTX-M

Methicillin
- MRSA

PAN SEPSIS PANEL (MODEL NO:- PG/IVD/SP-002)

Bacterial Species

Gram Negative Bacteria
- E coil
- Enterobacteriaceae
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
- Acinetobacter baumannii
- Proteus mirabills
- Salmonella species
- Neisseria meningitidis
- Haemophilus influenzae

Gram Positive Bacteria
- Staphylococcus pneumoniae
- Staphylococcus aglactecia
- Lysteria monocytogens
- strptococcus pyogenes
- Staphylococcus aureus
- Enterococcus faecalis
- Mycobacterium tuberculosis
- Staphylococcus saprophyticus

Fungus Species

Yeast
- Candida albicans
- Candida auris
- Candida galabrata
- Candida krusei
- Candida parapsilosis

Carbapenemase
- KPC
- NDM
- OXA-48
- OXA-23

Colistin
- MCR-1

ESBL
- CTX-M

Methicillin
- Mac A gene

PNEUMONIAE PANEL (MODEL PG/IVD/PN-001)

Gram Negative Bacteria
- Haemophilus influenzae
- Acinetobacter Baumannii
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
- Proteus mirabilis
- E.coli

Gram Positive Bacteria
- Streptococcus pneumoniae
- Streptococcus agalactia
- Staphylococcus aureus

AMR
- KPC
- NDM
- OXA-48
- OXA-23
- MEC
- CTX-M

NEONATAL SEPSIS PANEL

Gram Negative Bacteria
- Escherichia coli
- Serratia marcescens
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
- Acinetobacter baumannii

Gram Positive Bacteria
- Streptococcus pneumoniae
- Streptococcus agalactiae (GBS)
- Staphylococcus aureus
- Staphylococcus epidermis (CoNS)

AMR
- KPC
- NDM
- OXA-48
- OXA-23

CTX-M

Mec A gene

Van A

SMART FUNGUS PANEL

- Candida Albicans
- Candida auris
- Aspergillus fumigatus
- Rhizopus

PAN FUNGUS PANEL

Yeast:
- Candida Albicans
- Candida glabrata
- Candida auris
- Candida tropicalis
- Candida parapsilosis
- Candida krusei

Mould:
- Aspergillus fumigatus
- Rhizopus
- Mucor

PAN CANDIDA SPECIES PANEL

Yeast:
- Candida Albicans
- Candida glabrata
- Candida auris
- Candida tropicalis
- Candida Krusei
- Candida Parapsilosis

- XDR
- Rifampicin
- IS6110
- MPB64
- 16S rRNA

SMART GI PANEL

-  Shigella dysenteriae
- Salmonella TTR
- Vibrio cholerae
- Escherichia coli O157

PAN GASTROINTESTINAL (GI) PANEL

Bacteria
- Campylobacter jejuni
- Plesiomonas shigelloides
- Salmonella TTR
- Vibrio cholerae
- Yersinia enterocolitica

Diarrheagenic E.coli/Shigella
- Enteroaggregative E.coli (EAEC)
- Enteropathogenic E.coli (EPEC)
- Enterotoxigenic E.coli (ETEC)
- Shigella

SMART SKIN INFECTION PANEL

Bacteria
- Staphylococcus aureus
- Group A ẞ-hemolytic streptococci
- Candida Albicans

Diarrheagenic E.coli/Shigella
- Enteroaggregative E.coli (EAEC)
- Enteropathogenic E.coli (EPEC)
- Enterotoxigenic E.coli (ETEC)
- Shigella

SKIN INFECTION PANEL

Bacterial species
- Escherichia coli
- Staphylococcus aureus
- Coryneform bacteria
- Group A ẞ-hemolytic streptococci
- Klebsiella Pneumoniae
- Pseudomonas aeruginosa
- Enterococcus faecalis

Fungus Species
- Candida Albicans
- Aspergillus species

OSTEO-MYELITIS PANEL

Bacterial species
- Escherichia coli
- Klebsiella pneumoniae
- Pseudomonas aeruginosa

Gram Positive Bacteria
- Enterococcus faecalis
- Staphylococcus aureus
- Streptococcus agalactiae

AMR
- Mec A

Fungus Species
- Candida Albicans

VANCOMYCIN - RESISTANT ENTEROCOCCUS ( VRE) DETECTION KIT

- VAN A GENE

MRSA & S AUREUS DETECTION KIT (PRE- OPERATIVE TEST)

- Staphylococcus aureus
- MRSA

CANDIDA ALBICANS DETECTION KIT

- Candida Albicans

ASPERGILLUS FUMIGATUS DETECTION KIT

- Aspergillus Fumigatus

MUCORALES DETECTION KIT

- Mucor

RHIZOPUS DETECTION KIT

- Rhizopus homothallicus

CLOSTRIDIUM DIFFICILE DETECTION KIT

- Clostridium difficile

GROUP A STREPTOCOCCUS DNA DETECTION KIT

- Group a Streptococcus

CHOLERA DNA DETECTION KIT

- Vibrio cholerae

SHIGELLA DNA DETECTION KIT

- Shigella dysenteriae

SALMONELLA TYPHIMURIUM DNA DETECTION KIT

- Salmonella TTR
- STG gene

MENINGITIS DETECTION KIT*

- Addressing the urgent need for early detection of meningitis, this kit aims to improve treatment outcomes and reduce morbidity and mortality rates associated with the disease.

SEXUALLY TRANSMITTED DISEASE (STD) DETECTION KIT

- Providing discreet self-screening options for common STDs, this kit emphasizes the importance of professional medical consultation for accurate diagnosis and treatment.

MALARIA INFECTION DETECTION KIT*

- With a focus on endemic regions like India, this kit aims to improve malaria treatment outcomes by addressing drug-resistant strains through faster diagnostics.

LYMPHATIC FILARIASIS DETECTION KIT*

- Addressing the challenges of lymphatic filariasis diagnosis and treatment, this kit aims to enhance treatment efficiency through faster diagnostics.